近年来，在数字病理应用中，在研究和临床环境中越来越普遍的部署这些模型的部署证明了在数字病理应用中的深度学习模型的开发方面取得了巨大进步。尽管此类模型在解决DP应用程序中的基本计算任务方面表现出了前所未有的表现，但在适应转移学习的看不见数据时，它们会遭受灾难性的遗忘。随着对深度学习模型的需求越来越多地处理不断变化的数据分布，包括不断发展的患者人群和新的诊断测定法，持续的学习模型减轻了模型忘记的遗忘，需要在基于DP的分析中引入。但是，据我们所知，没有针对DP特定应用的此类模型的系统研究。在这里，我们提出了DP设置中的CL方案，其中的组织病理学图像数据来自不同来源/分布，其知识已集成到单个模型中，而无需从头开始训练所有数据。然后，我们建立了一个用于结直肠癌H＆E分类的增强数据集，以模拟图像外观的变化，并在拟议的CL方案中评估了CL模型性能。我们利用乳腺肿瘤H＆E数据集以及结直肠癌来评估不同肿瘤类型的CL。此外，我们在注释和计算资源的限制下在在线几弹性设置中评估了CL方法。我们揭示了DP应用中CL的有希望的结果，这可能为这些方法在临床实践中的应用铺平了道路。

When answering natural language questions over knowledge bases (KBs), incompleteness in the KB can naturally lead to many questions being unanswerable. While answerability has been explored in other QA settings, it has not been studied for QA over knowledge bases (KBQA). We first identify various forms of KB incompleteness that can result in a question being unanswerable. We then propose GrailQAbility, a new benchmark dataset, which systematically modifies GrailQA (a popular KBQA dataset) to represent all these incompleteness issues. Testing two state-of-the-art KBQA models (trained on original GrailQA as well as our GrailQAbility), we find that both models struggle to detect unanswerable questions, or sometimes detect them for the wrong reasons. Consequently, both models suffer significant loss in performance, underscoring the need for further research in making KBQA systems robust to unanswerability.

Search and Rescue (SAR) missions in remote environments often employ autonomous multi-robot systems that learn, plan, and execute a combination of local single-robot control actions, group primitives, and global mission-oriented coordination and collaboration. Often, SAR coordination strategies are manually designed by human experts who can remotely control the multi-robot system and enable semi-autonomous operations. However, in remote environments where connectivity is limited and human intervention is often not possible, decentralized collaboration strategies are needed for fully-autonomous operations. Nevertheless, decentralized coordination may be ineffective in adversarial environments due to sensor noise, actuation faults, or manipulation of inter-agent communication data. In this paper, we propose an algorithmic approach based on adversarial multi-agent reinforcement learning (MARL) that allows robots to efficiently coordinate their strategies in the presence of adversarial inter-agent communications. In our setup, the objective of the multi-robot team is to discover targets strategically in an obstacle-strewn geographical area by minimizing the average time needed to find the targets. It is assumed that the robots have no prior knowledge of the target locations, and they can interact with only a subset of neighboring robots at any time. Based on the centralized training with decentralized execution (CTDE) paradigm in MARL, we utilize a hierarchical meta-learning framework to learn dynamic team-coordination modalities and discover emergent team behavior under complex cooperative-competitive scenarios. The effectiveness of our approach is demonstrated on a collection of prototype grid-world environments with different specifications of benign and adversarial agents, target locations, and agent rewards.

With the steady emergence of community question answering (CQA) platforms like Quora, StackExchange, and WikiHow, users now have an unprecedented access to information on various kind of queries and tasks. Moreover, the rapid proliferation and localization of these platforms spanning geographic and linguistic boundaries offer a unique opportunity to study the task requirements and preferences of users in different socio-linguistic groups. In this study, we implement an entity-embedding model trained on a large longitudinal dataset of multi-lingual and task-oriented question-answer pairs to uncover and quantify the (i) prevalence and distribution of various online tasks across linguistic communities, and (ii) emerging and receding trends in task popularity over time in these communities. Our results show that there exists substantial variance in task preference as well as popularity trends across linguistic communities on the platform. Findings from this study will help Q&A platforms better curate and personalize content for non-English users, while also offering valuable insights to businesses looking to target non-English speaking communities online.

We derive a learning framework to generate routing/pickup policies for a fleet of vehicles tasked with servicing stochastically appearing requests on a city map. We focus on policies that 1) give rise to coordination amongst the vehicles, thereby reducing wait times for servicing requests, 2) are non-myopic, considering a-priori unknown potential future requests, and 3) can adapt to changes in the underlying demand distribution. Specifically, we are interested in adapting to fluctuations of actual demand conditions in urban environments, such as on-peak vs. off-peak hours. We achieve this through a combination of (i) online play, a lookahead optimization method that improves the performance of rollout methods via an approximate policy iteration step, and (ii) an offline approximation scheme that allows for adapting to changes in the underlying demand model. In particular, we achieve adaptivity of our learned policy to different demand distributions by quantifying a region of validity using the q-valid radius of a Wasserstein Ambiguity Set. We propose a mechanism for switching the originally trained offline approximation when the current demand is outside the original validity region. In this case, we propose to use an offline architecture, trained on a historical demand model that is closer to the current demand in terms of Wasserstein distance. We learn routing and pickup policies over real taxicab requests in downtown San Francisco with high variability between on-peak and off-peak hours, demonstrating the ability of our method to adapt to real fluctuation in demand distributions. Our numerical results demonstrate that our method outperforms rollout-based reinforcement learning, as well as several benchmarks based on classical methods from the field of operations research.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

肾细胞癌（RCC）是一种常见的癌症，随着临床行为的变化。懒惰的RCC通常是低级的，没有坏死，可以在没有治疗的情况下监测。激进的RCC通常是高级的，如果未及时检测和治疗，可能会导致转移和死亡。虽然大多数肾脏癌在CT扫描中都检测到，但分级是基于侵入性活检或手术的组织学。确定对CT图像的侵略性在临床上很重要，因为它促进了风险分层和治疗计划。这项研究旨在使用机器学习方法来识别与病理学特征相关的放射学特征，以促进评估CT图像而不是组织学上的癌症侵略性。本文提出了一种新型的自动化方法，即按区域（Corrfabr）相关的特征聚集，用于通过利用放射学和相应的不对齐病理学图像之间的相关性来对透明细胞RCC进行分类。 CORRFABR由三个主要步骤组成：（1）特征聚集，其中从放射学和病理图像中提取区域级特征，（2）融合，放射学特征与病理特征相关的放射学特征在区域级别上学习，并且（3）在其中预测的地方学到的相关特征用于仅使用CT作为输入来区分侵略性和顽固的透明细胞RCC。因此，在训练过程中，Corrfabr从放射学和病理学图像中学习，但是在没有病理图像的情况下，Corrfabr将使用CORFABR将侵略性与顽固的透明细胞RCC区分开。 Corrfabr仅比放射学特征改善了分类性能，二进制分类F1分数从0.68（0.04）增加到0.73（0.03）。这证明了将病理疾病特征纳入CT图像上透明细胞RCC侵袭性的分类的潜力。

近年来，地标复合物已成功地用于无定位和无公制的自主探索，并使用一组受GPS污染的环境中的一组感应有限的限制和沟通有限的机器人。为了确保快速而完整的探索，现有的作品对环境中地标的密度和分布做出了假设。这些假设可能过于限制，尤其是在可能被破坏或完全缺失的危险环境中。在本文中，我们首先提出了一个深入的加强学习框架，用于在具有稀疏地标的环境中，同时减少客户服务器交流的环境中的多代理合作探索。通过利用有关部分可观察性和信用分配的最新发展，我们的框架可以为多机器人系统有效地培训勘探政策。该政策从范围和分辨率有限的接近传感器基于近距离传感器的行动中获得个人奖励，该传感器与小组奖励相结合，以鼓励通过观察0-，1-维度和2维的简单来鼓励地标综合体的协作探索和建设。此外，我们采用三阶段的课程学习策略来通过逐渐增加随机障碍并破坏随机地标来减轻奖励稀疏性。模拟中的实验表明，我们的方法在不同环境之间具有稀疏地标的效率中的最先进的地标复杂探索方法。

在本文中，我们引入了一种半居中的控制技术，用于在不确定的遮挡环境中运送脆弱物体到目的地的一群机器人。建议的方法已分为两部分。初始部分（第1阶段）包括一种集中的控制策略，用于在代理之间创建特定的形成，以便可以将要运输的对象正确放在系统顶部。我们提出了一种与基于圆形区域的形状控制方法融合在一起的新型三角填料方案，用于在机器人之间创建刚性配置。在后面的部分（第2阶段），需要群体系统以采用基于区域的形状控制方法的分散方式将对象传达到目的地。模拟结果以及比较研究证明了我们提出的方案的有效性。

数字化和自动化方面的快速进步导致医疗保健的加速增长，从而产生了新型模型，这些模型正在创造新的渠道，以降低成本。 Metaverse是一项在数字空间中的新兴技术，在医疗保健方面具有巨大的潜力，为患者和医生带来了现实的经验。荟萃分析是多种促成技术的汇合，例如人工智能，虚拟现实，增强现实，医疗设备，机器人技术，量子计算等。通过哪些方向可以探索提供优质医疗保健治疗和服务的新方向。这些技术的合并确保了身临其境，亲密和个性化的患者护理。它还提供自适应智能解决方案，以消除医疗保健提供者和接收器之间的障碍。本文对医疗保健的荟萃分析提供了全面的综述，强调了最新技术的状态，即采用医疗保健元元的能力技术，潜在的应用程序和相关项目。还确定了用于医疗保健应用的元元改编的问题，并强调了合理的解决方案作为未来研究方向的一部分。